IL-18BP (C-Fc), Human, Recombinant

IL-18BP (C-Fc), Human, Recombinant





  • 10µg
  • 50µg
  • 500µg
  • 1mg

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别名 Interleukin-18-binding Protein; Tadekinig-alfa and IL18BP;
物种 Human
表达宿主 Human Cells
序列信息 asd
检索号 O95998
分子量 44.7 kDa
表观分子量 55 kDa
标签 C-Fc
生物活性 Testing in progress


纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.


Interleukin-18-binding Protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its Receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.
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