IL-21R/ CD360, Human, Recombinant
货号：PCK182
价格：¥680¥1380¥7880¥9980
规格：
10µg
- 10µg
- 50µg
- 500µg
- 1mg
- 产品概述
- 相关产品推荐
产品概述
产品信息
| 别名 | Interleukin-21 Receptor; IL-21 Receptor; IL-21R; CD360. |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | asd |
| 检索号 | Q9HBE5-1 |
| 分子量 | 26.0 kDa |
| 表观分子量 | 46 kDa |
| 标签 | C-6His |
| 生物活性 | Measured by its ability to bind human IL-21 in a functional ELISA. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 1-5 ng/ ml in the presence of 10 ng/ ml of recombinant human IL23. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 50-200 pg/ mL in the presence of 1 ng/ ml of recombinant human IL21. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH 7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Interleukin-21 Receptor is also known as IL-21 Receptor, IL-21R, CD360. In humans, it is encoded by the IL21R gene. It belongs to the type I Cytokine Receptor family. Type 4 subfamily contains 2 fibronectin type-III domains. Interleukin-21 Receptor is selectively expressed in lymphoid tissues and highly expressed in thymus and spleen. IL-21 is produced by CD4+ T cells in response to antigenic stimulation. Its action enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells. It also promotes the anti-tumor activity of CD8+ T-cells and NK cells.
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