IL-4Rα/ CD124 (C-mFc), Human, Recombinant

IL-4Rα/ CD124 (C-mFc), Human, Recombinant





  • 10µg
  • 50µg
  • 500µg
  • 1mg

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别名 Interleukin-4 Receptor subunit alpha; IL-4 Receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding Protein; IL4-BP; IL4R; IL4RA
物种 Human
表达宿主 Human Cells
序列信息 asd
检索号 P24394
分子量 50.2 kDa
表观分子量 65-86 kDa
生物活性 Testing in progress


纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
复融 Dissolve the lyophilized protein in distilled water.


Interleukin 4 Receptor alpha (IL4-Ra) is a widely expressed 140 kDa transmembrane glyco Protein in theclass I Cytokine Receptor family. Mature human IL4-Ra consists of a 207 amino acid (aa) extracellulardomain (ECD) that contains a Cytokine binding region and one fibronectin type III domain, a 24 aatransmembrane segment, and a 569 aa cytoplasmic domain that contains one Box 1 Motif and one ITIMMotif. IL4-Ra plays an important role in Th2-biased immune responses, alternative macrophage activation,mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. Soluble forms of IL4-Ra,generated by alternate splicing or proteolysis, retain Ligand binding properties and inhibit IL-4 bioactivity.
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