Interferon γ/ IFN-γ/ IFNG, Human, Recombinant


Interferon γ/ IFN-γ/ IFNG, Human, Recombinant

货号:PCK063

价格:¥780¥1880¥7880¥9980

规格:

10µg

  • 10µg
  • 50µg
  • 500µg
  • 1mg

  • 产品概述
  • 相关产品推荐

产品概述

产品信息

别名 Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG
物种 Human
表达宿主 Human Cells
序列信息 asd
检索号 P01579
分子量 16.8 kDa
表观分子量 16&20-25 kDa
生物活性 Measured by a viral resistance assay using VSV-WISH cells.Specific Activity is greater than 1.5?0^7 IU/ mg.

产品特性

纯度 >90% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.
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Interferon γ/ IFN-γ/ IFNG, Mouse, Recombinant


Interferon γ/ IFN-γ/ IFNG, Mouse, Recombinant

货号:PCK065

价格:¥880¥1880¥12680¥18680

规格:

10µg

  • 10µg
  • 50µg
  • 500µg
  • 1mg

  • 产品概述
  • 相关产品推荐

产品概述

产品信息

别名 Ifng; Interferon gamma; IFN-gamma
物种 Mouse
表达宿主 Human Cells
序列信息 asd
检索号 P01580
分子量 15.5 kDa
表观分子量 18 kDa
生物活性 Testing in progress

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Mouse Ifng is a secreted Protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete Cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
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