NT3/ NGF-2, Human, Recombinant
货号:PCK210
价格:¥1780¥4980¥17280¥25680
规格:
10µg
- 10µg
- 50µg
- 500µg
- 1mg
- 产品概述
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产品概述
产品信息
别名 | Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3 |
物种 | Human |
表达宿主 | E.coli |
序列信息 | asd |
检索号 | P20783 |
分子量 | 13.6 kDa |
表观分子量 | 14 kDa |
生物活性 | Measured by its ability to bind Human NTRK2 in functional ELISA. The ED50 for this effect is less than 10 ug/ ml. |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
内毒素 | < 1.0 EU per µg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor Protein with a signal peptide and a pro Protein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.
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